Association between human papillomavirus type 18 variants and histopathology of cervical cancer.

Laminin molecular domains which alter me-tastasis in a murine model.bel ME. Modulation of laminin receptor expression by estrogen and progestins in human breast cancer cell lines. Prognostic significance of the 67-kilodalton laminin receptor expression in human breast carcinomas. Laminin receptors, collagenase IV and prognosis in node-negative breast cancers.nostic significance of laminin production in relation with its receptor expression in human breast carcinomas. Expression of a Mr 32,000 laminin-binding protein messenger RNA in human colon carcinoma correlates with disease progression. Increased expression of the laminin receptor in human colon cancer.tection of laminin receptor mRNA in human cancer cell lines and colorectal tissues by in situ hybridization. WF. Augmentation of type IV collagenase, laminin receptor, and ki67 proliferation anti-gen associated with human colon, gastric, and breast carcinoma progression.pression of the 67 kD laminin receptor in human ovarian carcinomas as defined by a monoclonal antibody, MLuC5. Expression of high-affinity laminin receptor mRNA correlates with cell proliferation rather than invasion in human papillomavirus-associated cervical neo-plasms.pression of the 67kDa-laminin receptor gene in human small cell lung cancer. Expression of the 67 KD laminin receptor is an adverse prognostic indicator in human thyroid cancer: immunohistochemical study. al. Evaluation of hepatocellular carcinoma aggressiveness by a panel of extracellular matrix antigens.tivity of a monoclonal antibody with tissues and tumors from the human breast. Immuno-histochemical localization of a new antigen and clinicopathologic correlations. Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging. Notes Supported in part by a grant from the National Fund for Scientific Research (Belgium). We thank Laragh Gollogly for her technical assistance , Walthere Dewe for his statistical work, and Mark E. Sobel for his evaluation of the manuscript. Adenocarcinoma, adenosquamous carcinoma, and small-cell carcinoma of the uterine cervix are reported to be low in incidence but clinically important. They usually exhibit a more aggressive biologic behavior and have a poorer prognosis than squamous cell carcino-mas at similar stages (1–3). Although human papillomavirus type 16 (HPV16) is associated predominantly with squa-mous cell carcinomas and HPV18 is associated predominantly with adeno-carcinomas and adenosquamous carci-nomas (4), differences in prognosis among these groups of cancers are largely still not understood. On the other hand, few reports have evaluated the role of HPV type in the development of small-cell carcinomas [e.g., (5)]. DNA sequence variations among different isolates of HPV16 and HPV18 have been found in various geographic locations and ethnic groups (6–11). To date, these …